AVS11 Program (subject to change)

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Monday 5 December
2:30 - 4:30pm Registration
Poster Set Up
Level 2 Foyer
4:30 - 4:45pm Welcome and Official Opening
AVS11 Meeting Convenor, Assoc Prof Lara Herrero
AVS President, Prof Heidi Drummer
Grand Ballroom
4:45 - 5:15pm AVS Over the Years
Prof Paul Young, The University of Queensland

Chair: Assoc Prof Lara Herrero, Griffith University
Grand Ballroom
5:15 - 6:15pm International Guest Speaker
Structure-based Immunogen Design
Prof Jason McLellan, University of Texas, Austin USA
Chair: Prof Paul Young, The University of Queensland
With thanks to our Opening Keynote Sponsor
Grand Ballroom
Welcome Mixer
As a nod to the fi rst ever AVS Meeting, we invite you to don a Hawaiian/ colourful shirt for the Welcome Mixer.
A prize to be won for the ‘loudest’ shirt of the night!
With thanks to our Welcome Mixer Sponsor
JW Marriott, Poolside
Tuesday 6 December
8:30 - 10:00am Session 1: Animal and Wildlife Viruses
Chairs:
Dr Glenn Marsh, CSIRO
Dr Turgut Aktepe, University of Melbourne, Melbourne Veterinary School

Invited Speaker:
Uncovering the viromes of fish, amphibians and reptiles using metatranscriptomics and metagenomics
Prof Peter White, University of New South Wales

Unearthing the diversity of ancient retroviruses in Australian marsupials
Emma Harding, UNSW Sydney

Latid herpesvirus 1 — a novel virus that could threaten the Australian barramundi industry
Lewis Mercer, UNSW Sydney

Koala retrovirus genetic diversity and transmission dynamics within captive koala populations
Briony Joyce, The University of Queensland

Metagenomic detection and characterisation of many viruses, including human adenoviruses, in apparently healthy Australian Neophema birds
Subir Sarker, La Trobe University
Grand Ballroom
10:00 - 10:30am Morning Refreshments Tambourine & Ballroom Foyers
10:30 - 12:00pm Session 2: Innate Immunity
Chairs:
Prof Michael Beard, University of Adelaide
Dr Svenja Fritzlar, The University of Melbourne

Invited Speaker:
Leveraging airway innate immunity to protect against respiratory viruses
Assoc Prof Nathan Bartlett, University of Newcastle

Targeting viral immune evasion for attenuated ‘live’ vaccine design
Greg Moseley, Monash University

Lipid droplets contribute to an antiviral bystander effect during infection
Ebony Monson, La Trobe University

P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection
Florian I Schmidt, University of Bonn

Exploring TRIM proteins as targets for broad spectrum antivirals
Rubaiyea Farrukee, The University of Melbourne
Grand Ballroom
12:00 - 1:00pm Lunch Tambourine & Ballroom Foyers
12:15 - 12:45pm ECR - Meet the Professors Grand Ballroom
1:00 - 2:30pm Session 3: Antivirals and vaccines
Chairs:
Assoc Prof Branka Grubor, University of Adelaide
Dr Emma Grant, La Trobe University
With thanks to our Session Sponsor


Invited Speaker:
Rational treatment strategies for SARS-CoV-2 derived from studies in human pluripotent stem cell models
Prof Kanta Subbarao, The Peter Doherty Institute for Infection and Immunity

Incorporation of SARS-CoV-2 Spike NTD to RBD-Based Vaccine Improves Immunity and Protection Against Variants of Concern
Lisa Connor, Victoria University of Wellington

Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques
Brendon Chua, The University of Melbourne

A Platform Technology for Generating Subunit Vaccines Against Diverse Viral Pathogens
Andrew Young, The University of Queensland

A combination of molnupiravir and oseltamivir is superior to either drug alone for the treatment of influenza in ferrets
Paulina Koszalka, WHO Collaborating Centre for Reference and Research on Influenza
Grand Ballroom
2:30 - 3:00 Afternoon Refreshments Tambourine & Ballroom Foyers
3:00 - 4:30 Session 4: Virus Structures, Receptors, Assembly and Replication
Chairs:
Assoc Prof Daniel Waterson, University of Queensland
Alice Trenerry, University of Melbourne

Invited Speaker:
Structural basis for MERS-CoV ORF4b binding to the nuclear import receptor imp-alpha
Prof Jade Forwood, Charles Sturt University

Investigation of SARS-CoV-2 Variants of Concern to identify determinants of transmissibility and virulence
Andrew Davidson, University of Bristol

Live Cell Imaging of Hepatitis B Virus covalent closed circular DNA
Xiaonan Zhang, University of Canberra

Near-Atomic Structures of Emerging Japanese Encephalitis Virus Genotypes Reveal Important Epitope & Antigenic Differences
Morgan Freney, The University of Queensland

Envelope protein domain III is a key determinate of Yellow Fever Virus structure
Summa Bibby, The University of Queensland
Grand Ballroom
4:30 - 5:00 Free Time
5:00 - 6:00pm International Guest Speaker
Understanding pandemic viruses
Prof Wendy Barclay, Imperial College, London

Chair:
Dr Sarah Londrigan, The University of Melbourne
Grand Ballroom
6:00 - 6:30pm Science Bites
Chairs:
Camille Esneau, University of Newcastle
Wesley Freppell, Griffith University

Immune Priming as a Strategy to Prevent HaHV-1 Infection in Australian Abalone
Jacinta Agius, La Trobe University

Identifying introduced and novel viruses in small mammals on the island of Tasmania
Erin Harvey, The University of Sydney

The Interactions between Probiotic Bacteria and Respiratory Viruses within the Epithelium of the Upper Respiratory Tract
Tejasri Yarlagadda, The Queensland University of Technology

Tetravalent microprojection-based dengue chimeric virus vaccine raises potent neutralising antibodies in mice
Jovin Choo, The University of Queensland

Mitigating the risk of infectious virus in aerosols
Leo Lee, The University of Melbourne

Rapid, isothermal detection of Zika virus: a potential alternative to RTPCR
Rickyle Balea, The University of the Sunshine Coast

Reconstructing ancestral flaviviruses to fight current and future flavivirus outbreaks
Natalee Newton, The University of Queensland

The Middle East Respiratory Syndrome Coronavirus ORF4b binds host importin alpha isoforms via an unusual mechanism to inhibit innate immunity
Thilini Surenika Munasinghe, School of Dentistry and Medical Sciences, Charles Sturt University
Grand Ballroom
6:30 - 7:30pm Poster Session | Refreshments served
With thanks to our Poster Session Sponsor
Tambourine Gallery
Wednesday 7 December
7:00 - 8:00am Breakfast Session
CV Builder for ECRs
Prof Katherine Andrews, Griffith University
With thanks to our ECR Career Development Sponsor
Grand Ballroom
8:30 - 10:00am Session 5: Viral Epidemiology and Diagnostics
Chairs:
Prof Peter White, UNSW Sydney
Dr Bethany Horsburgh, Kirby Institute
With thanks to our Session Sponsor


Invited Speaker:
Infectious Diseases in Africa: Friend or Foe
Dr Belinda Herring, WHO Regional Office for Africa

Integration of innovative platform technologies for the diagnosis of flaviviral infections
Ryan Johnston, The University of Queensland

Development of a novel adaptable whole genome sequencing assay for HIV and HCV
Bethany Horsburgh, Kirby Institute

The Host Response as a Novel Diagnostic Biomarker for ‘PreSymptomatic’ COVID-19
Georgina McCallum, The University of Queensland

A novel chimeric virus for vaccine and diagnostic application for the Japanese encephalitis virus outbreak in Australia
Jessica Harrison, University of Queensland
Grand Ballroom
10:00 - 10:30am Morning Refreshments Tambourine & Ballroom Foyers
10:30 - 12:00pm Session 6: Systems Virology and Viromes
Chairs:
Prof Andrew Harman, University of Sydney
Dr Rhys Parry, The University of Queensland

Invited Speaker:
Towards an understanding of virus ecology in wildlife: from “one hostone virus” models to viromes
Dr Michelle Wille, The University of Sydney

Illuminating the unseen majority beneath our feet – enumeration of the global virome using intelligent algorithms
Richard Allen White III, UNCC

The lipidome of lipid droplets changes significantly during viral infection in the brain 
Zahra Telikani, La Trobe University

Dengue virus evolution to Wolbachia; a potential Achilles’ heel
Kathryn Edenborough, Monash University

Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis
Andrii Slonchak, The University of Queensland
Grand Ballroom
12:00 - 1:30pm Lunch Tambourine and Ballroom Foyers
12:15 - 1:15pm Panel session for ECRs on career development
Belinda Herring WHO, Simone Vink Davies Collison Cave, Julianne Bayliss CSL, Miguel Quinones-Mateu The University of Otago, Tony Cunningham University of Sydney, Katherine Andrews Griffi th University
Chair: Emma Harding, UNSW Sydney
With thanks to our ECR Career Development sponsor
Grand Ballroom
1:30 - 3:00pm Session 7: Viral Host Interactions
Chairs:
Assoc Prof Jill Carr, Flinders University
Dr Ebony Monson, La Trobe University

Invited Speaker:
Exploring dengue virus (DENV) NS1 protein biology and antiviral drug development using infectious tagged reporter viruses
Dr Nicholas Eyre, Flinders University

MicroRNAs: Macro Roles in Insect Host-Virus Interactions?
Daniel Chew, The University of Queensland

New insights into the dynamics of sexual transmission of HIV
Andrew Harman, University of Sydney

Using natural history to determine the risk of dengue virus escape from Wolbachia in Aedes aegypti mosquitoes
Johanna Fraser, Monash University

Does SARS-CoV-2 infect the brain? Evidence of in-host neurotropic adaptation and ACE2-independent infection
Daniel Rawle, QIMR Berghofer Medical Research Institute
Grand Ballroom
3:00 - 3:30pm Afternoon Refreshments Tambourine & Ballroom Foyers
3:30 - 5:00pm Session 8: Viral Immunology
Chairs:
Prof Allison Abendroth, The University of Sydney
Dr Jennifer Juno, The University of Melbourne
With thanks to our Session Sponsor


Invited Speaker:
CD8+ T cell immunity in viral infection and vaccination Prof Katherine Kedzierska, The Peter Doherty Institute for Infection & Immunity

Mucosal inflammatory and antibody responses associated with protection and disease after human SARS-CoV-2 challenge
Ryan Thwaites, Imperial College London

Influenza-specific CD8+ T cells across the human lifespan: a suboptimal reset for the elderly
Carolien Van De Sandt, University of Melbourne

Immune responses in the respiratory tract and blood of COVID-19 patients reveal mechanisms of disease severity
Wuji Zhang, University of Melbourne

Characterising the Initial Events of Herpes Simplex Virus Infection in Human Anogenital Tissue
Hafsa Rana, Westmead Institute for Medical Research
Grand Ballroom
5:00 - 5:30pm Science Bites
Chairs:
Camille Esneau, University of Newcastle
Wesley Freppell, Griffith University

Identification of dengue virus (DENV) NS1 protein residues that are critical to its secretion
Brandon E K Tan, University of Adelaide

Structural characterisation of the lyssavirus N0P complex reveals a highly conserved interface
Camilla Donnelly, Charles Sturt University/CSIRO Post Graduate Student

TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection
Meisam Yousefi, Duke-NUS Medical School

A new recombinant alphavirus platform based on the insect-specific Yada Yada virus
Mikaela Bell, The University of Queensland

Lagovirus protein p23 is a viroporin
Elena Smertina, CSIRO

Neuropathogenesis: Mousing around with henipaviruses
Sarah Edwards, CSIRO

Characterising inflammatory mechanisms in long COVID
Jane Sinclair, The University of Queensland, School of Chemistry and Molecular Bioscience

Repurposed MCC950 and VX-765 provide survival advantage in prophylactically treated SARS-CoV-2 infected K18-hACE2 mice
Aroon Supramaniam, Menzies Health Institute Queensland
Grand Ballroom
5:30 - 6:30pm Poster Session | Refreshments served
With thanks to our Poster Session Sponsor
Tambourine Gallery
Thursday 8 December
7:45 A light breakfast of croissants, tea and coffee served in the Ballroom foyer
8:00 - 9:00am Session 9 (a): Antiviral and Vaccines II
Chair:
Prof Karla Helbig, La Trobe University

T cell vaccines against Zika virus
Branka Grubor-Bauk, University of Adelaide

SARS-CoV-2 virus-like particles as a candidate for the second generation of vaccines against COVID-19
Julio Carrera-Montoya, University of Melbourne

Engineered cellular exosome therapeutics to treat viral infections
Kevin Morris, Griffith University

Micro-projection Array Patch Delivery of Measles and Rubella Vaccine in a Phase I Clinical Trial
Imogen Bermingham, Vaxxas Pty Ltd

Ballroom 1
Session 9 (b): Viral Immunology II
Chair:
Assoc Prof Rowena Bull, UNSW Sydney

COVID-19 vaccination induces robust SARS-CoV-2 T cell responses in blood cancer patients in the presence and absence of B cells
Oanh Nguyen, The University of Melbourne

A broadly applicable subunit vaccine platform to safeguard against future viral pandemics
Keith Chappell, University of Queensland

Influenza virus infection induces high levels of CD52 expression on effector CD8+ T cells in the infected lung
So Young Chang, The University of Melbourne, Peter Doherty Institute for Infection and Immunity

Increased immunopathology and perturbed immune dynamics during influenza virus and arbovirus co-infection
Isabelle Foo, The Peter Doherty Institute for Infection and Immunity
Ballroom 2
9:00 – 10:00 Session 10 (a): Viral host interactions II
Chair:
Assoc Prof Lara Herrero, Griffith University

Host glycocalyx captures HIV proximal to the cell surface via oligomannose-GlcNAc glycan-glycan interactions to support viral entry
Belinda De Villiers, Griffith University, Institute for Glycomics

Unravelling the antiviral mechanisms by which Wolbachia pipientis restricts dengue virus replication
Robson Kriiger Loterio, Monash University

Digital spatial profiling of the immune influx that occurs during chikungunya virus and o’nyong nyong virus infections
Penny A Rudd, Griffith University

Modulation of CD81 by the E3 ubiquitin ligase MARCH8 inhibits replication of HSV-1 – a novel mechanism of MARCH8-mediated virus restriction
Patrick Reading, Who Collaborating Centre for Reference and Research on Influenza
Ballroom 1
Session 10 (b): Innate Immunology II
Chair:
Dr Sarah Londrigan, The University of Melbourne

The multifaceted attack on MR1 antigen presentation by herpes simplex viruses
Carolyn Samer, University of Sydney

A novel mouse upper respiratory tract infection model with human coronavirus OC43 defines IFN-λ expression and TLR2/6 mediated innate immune activation
Nathan Bryant, University of Newcastle

Varicella Zoster Virus infects and functionally hijacks Mucosal Associated Invariant T cells
Shivam Purohit, University of Sydney

Lipid droplets act as platforms for innate immune signalling proteins
Jay Laws, La Trobe University
Ballroom 2
10:00 - 10:30am Morning Refreshments Tambourine & Ballroom Foyers
10:30 - 12:00pm Session 11: Unusual Viruses, Phages and Plant Viruses
Chairs:
Dr Jody Peters, The University of Queensland
Dr Stephanie Lynch, Westmead Institute for Medical Research
With thanks to our Session Sponsor


Invited Speaker:
Sequence to biology of fungal and phytophthora viruses
Assoc Prof Robin MacDiarmid, The New Zealand Institute for Plant & Food Research Limited

Structural insights into the origins and lifestyle of persistent plant partitiviruses
Frank Sainsbury, Griffith University

Jingmenviruses: ubiquitous, understudied, segmented flavi-like viruses
Agathe Colmant, Aix-Marseille University

Meta-transcriptomic analysis of wild animal gut content is a useful strategy for the surveillance of plant pathogens in Australia
Jackie Mahar, University of Sydney

Evolution of grapevine leafroll-associated virus 3: genetic diversity and virulence
Roshni Rohra, The New Zealand Institute of Plant & Food Research Ltd
Grand Ballroom
12:00 - 1:15pm Lunch Tambourine & Ballroom Foyers
12:15 - 1:15pm AVS AGM Grand Ballroom
1:15 - 2:45pm Session 12: Focus on virology in First Nation communities
Chairs:
Prof Jason Mackenzie, The University of Melbourne
Dr Louise Rowntree, The University of Melbourne
With thanks to our Session Sponsor


Invited Speaker:
Prof James Ward, The University of Queensland

Chronic immune activation and T-cell dysfunction mediated from the HTLV-1c provirus graveyard
Ashley Hirons, The University of Melbourne

Working towards 95% coverage for influenza-specific CD8+ T cell immunity in Indigenous Australians
Louise Rowntree, The University of Melbourne

Robust and prototypical immune responses towards COVID-19 BNT162b2 vaccine in First Nations Australian people can be impacted by comorbidities
Wuji Zhang, University of Melbourne

Structure of the HTLV-1 Capsid Reveals a Druggable Pocket
David Jacques, UNSW Sydney
Grand Ballroom
2:45 - 3:15pm Afternoon Refreshments Tambourine & Ballroom Foyers
3:15 - 4:45pm Session 13: Clinical Virology
Chairs:
Prof Tony Cunningham, The Westmead Institute for Medical Research
Dr Ki Wook Kim, UNSW Sydney

Invited Speaker:
HTLV1 a neglected cause of morbidity and mortality

Assoc Prof Lloyd Einsiedel, Doherty Institute

Does Human Papillomavirus use a ‘Hit and Run’ mechanism in head and neck cancer pathogenesis?
Danyelle Ferreira, Griffith University

Phage Australia: Building a phage therapy centre
Stephanie Lynch, Westmead Institute for Medical Research

Identifying the neurological impact of COVID-19 in a mouse of model of SARS-CoV-2 infection
Julie McAuley, The University of Melbourne

A role for gut barrier breakdown in severe dengue disease
Kate Stacey, University of Queensland
Grand Ballroom
4:45 - 5:00pm AVS11 Meeting Concludes Grand Ballroom
7:15pm AVS11 Dinner
If you have booked a ticket for the dinner, you will have a knife and fork icon on your name badge. Dress: Smart casual
Grand Ballroom